Chest
Selected ReportsAcute Pneumonitis with Bilateral Pleural Effusion after Talc Pleurodesis
Section snippets
CASE REPORT
A 40-year-old woman was admitted to the Intensive Care Unit, in May 1982, because of rapidly progressing dyspnea following talc pleurodesis for recurrent right pleural effusion. In 1971, a complete remission of stage 2 Hodgkin's disease was obtained by chemotherapy and radiotherapy. In 1972, she was treated for radiation-induced pericardial tamponade. She was well during 1972-76, but was hospitalized several times during 1976-81 with recurrent right pleural effusion considered to be secondary
DISCUSSION
The patient just reported presented a distinct and unusual clinical syndrome. A few hours after talc pleurodesis, she developed fever with malaise and dyspnea that was rapidly followed by acute respiratory failure. Chest x-ray film findings consisted of bilateral pleural effusion with interstitial infiltrates. Analysis of arterial blood gas showed compromised gas exchange with severe hypoxemia, and right-sided cardiac catheterization disclosed a slight increase in pulmonary arterial pressure.
ACKNOWLEDGMENT
We are indebted to Dr. V. J. Ferrans for advice and criticism, to Misses M. Grandsaigne and F. Mazin for technical assistance; and to Miss S. Rimbault for assistance in the preparation of the manuscript.
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