Regular ArticleThe Use of a D-dimer Assay in Patients Undergoing CT Pulmonary Angiography for Suspected Pulmonary Embolus
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Cited by (23)
D-dimer in the diagnostic workup of suspected pulmonary thrombo-embolism at high altitude
2012, Medical Journal Armed Forces IndiaCitation Excerpt :The true benefits of the D-dimer assay lie in its NPV, which, in turn, translates into cost savings by eliminating the need for expensive imaging exams for negative low-risk patients. These patients are able to avoid invasive testing to rule out PTE.10 On the other hand, a positive result leads to additional testing to rule out or diagnose PTE.
Cost-effectiveness of strategies for diagnosing pulmonary embolism among emergency department patients presenting with undifferentiated symptoms
2010, Annals of Emergency MedicineCitation Excerpt :Cutoff III (500 μg/L) represents the current widely used cutoff for the Vidas ELISA D-dimer (Table 2).14,16,30,37,40-42,44,77-80 We estimated computed tomographic venogram, compression ultrasonography, and computed tomographic pulmonary angiogram sensitivity and specificity from the literature.15,27,28,30,67,69,70,81-95 Ventilation-perfusion scan scan performance for pulmonary embolism at each ventilation-perfusion scan cutoff value considered (low, normal, intermediate) has been extensively studied.51,92,95-98
Abnormal D-Dimer and Negative Computed Tomography Scan Results Do Not Exclude a Pulmonary Embolus [4]
2004, Annals of Emergency MedicineClinical utility of d-dimer in patients with suspected pulmonary embolism and nondiagnostic lung scans or negative CT findings
2004, ChestCitation Excerpt :The reason for this difference is likely the higher prevalence of acute or chronic conditions associated with fibrin generation among the inpatients, such as a history of recent surgery, myocardial infarction, or cancer (Table 1). Most previous studies of d-dimer in patients with suspected pulmonary embolism have included entirely or mostly outpatients,16171819202122 or failed to report the mix of inpatients and outpatients in the study population. The frequency of a negative d-dimer result among our outpatients is consistent with these prior studies.161718192021
Venous thromboembolic disease: Where does multidetector computed tomography fit?
2003, Cardiology ClinicsValue of Quantitative D-dimer Assays in Identifying Pulmonary Embolism: Implications from a Sequential Decision Model
2006, Academic Emergency MedicineCitation Excerpt :Initial CUS sensitivity for DVT was set at 0.93, with specificity of 0.98.14,32–35 Initial CTP sensitivity was 0.9, with specificity of 0.8.9,10,23,36–40 We performed extensive univariate and multivariate sensitivity analysis on CTP and CTV sensitivity and specificity.
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Author for correspondence and guarantor of study: Dr S. P. G. Padley, Department of Radiology, Chelsea and Westminster Hospital, 369 Fulham Road, London, SW10 9NH, U.K. Fax: + 44 (0) 020 8746 8588; E-mail: [email protected]