Asthma diagnosis and treatmentMode of delivery at birth and development of asthma: A population-based cohort study
Section snippets
Study design and setting
The study was a retrospective, population-based cohort study.
Rochester, Minn, is centrally located in Olmsted County, and greater than 60% of the county population resides within the city limits. In 1980, the population of Rochester was 57,890 (97% white). With the exception of a higher proportion of the working population employed in the health care industry, characteristics of the City of Rochester and Olmsted County populations were similar to those of the US white population.36, 37, 38
Incidence cohort
During the period 1976 to 1982, 7463 children were born to mothers who were residents of the City of Rochester at the time of their delivery. Of these children, 21 children died, 324 children were born after prolonged rupture of membranes, and 12 were born after the vaginal procedure was converted to a cesarean section, yielding 7106 children in the birth cohort who met the study criteria. Of the remaining 7106 children, a total of 342 met the criteria for either definite or probable asthma
Discussion
Our study results show that mode of delivery at birth was not associated with risk of subsequent development of childhood asthma or wheezing episodes in the 1976 to 1982 Rochester birth cohort during their first 7 years of life. However, as depicted in Table III, the relationship between childhood asthma or wheezing episodes and mode of delivery at birth is not constant but varies over time.
According to our study results, during the first 2 years of life or so, children born by cesarean section
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Supported by the Scholarly Clinician Award of the Mayo Foundation.
Disclosure of potential conflict of interest: All authors—none disclosed.