Original articleLongitudinal changes in atopy during a 4-year period: Relation to bronchial hyperresponsiveness and respiratory symptoms in a population sample of Australian schoolchildren☆
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2017, Annals of Allergy, Asthma and ImmunologyCitation Excerpt :However, our knowledge of changes over time in reactivity and the clinical implications of sensitization to the different groups of aeroallergens (ie, pollen, fur, house dust mites, and mold) remains limited. The few longitudinal studies completed have mostly observed the study population for a period of 2 to 8 years and found that sensitization is developed through childhood and puberty12,13 and lost in late adulthood.14 The aim of the present study was, therefore, to examine the change in SPT reactivity in a random population sample of children and adolescents during a 20-year period.
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2017, Journal of Allergy and Clinical ImmunologyIncrease in Allergic Sensitization in Schoolchildren: Two Cohorts Compared 10 Years Apart
2017, Journal of Allergy and Clinical Immunology: In PracticeCitation Excerpt :In Australia, the 4-year incidence was 15%,16 while a lower incidence was reported from Isle of Wight, 14%, over 6 years.15 However, completely accurate comparisons are difficult because the ages under study and the studied allergens differ somewhat.15,16 Interestingly, in our study area, the incidence of allergic sensitization from age 7 to 8 years to age 11 to 12 years had increased significantly from 14% to 18% over 10 years.
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Supported by the Asthma Foundation of New South Wales and National Health and Medical Research Council of Australia.
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Senior Research Assistant.
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Professor of Respiratory Medicine.