Original article
Endotoxin activity of a house dust extract

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Abstract

A commercial dust extract has been demonstrated to contain endotoxin-like activity. The clinical significance of this finding is unclear, but any substance as biologically active as endotoxin must be seriously considered to have some action when it is injected into a living organism. Any study of the action of dust extract in clinical allergy must consider this potent substance.

References (27)

  • W.E. Vannier et al.

    A Starch Block Electrophoresis Study of Aqueous House Dust Extracts

    J. Allergy

    (1961)
  • J.E. Gundy

    Acellular Bacterial Antigen Complex in the Treatment of Children With Recurrent Respiratory Infections and Infectious Asthma

    J. Pediat

    (1957)
  • L. Berrens et al.

    Purification and Properties of House Dust Allergen

    Internat. Arch. Allergy

    (1961)
  • J. Glaser

    Allergy in Childhood

  • R.J. Dubos et al.

    Reversible Changes in the Susceptibility of Mice to Bacterial Infections

    J. Exper. Med

    (1956)
  • D. Pressman et al.

    The Agglutination of Intact Azo-Erythrocytes by Antisera Homologous to the Attached Groups

    J. Immunol

    (1942)
  • J. Gordon et al.

    Detection of “Non-precipitating” Antibodies in Sera of Individuals Allergic to Ragweed Pollen by an In Vitro Method

    J. Exper. Med

    (1958)
  • E.V. Staab et al.

    Studies on the Biologic Relationship of Endotoxin and Other Toxic Proteins. II. Enhancement of Susceptibility to Snake Venom by Endotoxin

    J. Exper. Med

    (1962)
  • H.F. Swift et al.

    Typing Group A Hemolytic Streptococci by M Precipitin Reactions in Capillary Pipettes

    J. Exper. Med

    (1943)
  • A.J. Crowle

    A Simplified Micro Double-Diffusion Agar Precipitin Technique

    J. Lab. & Clin. Med

    (1958)
  • D.W. Watson et al.

    Modification of Host Response to Bacterial Endotoxins. I. Specificity of Pyrogenic Tolerance and the Role of Hypersensitivity in Pyrogenicity, Lethality, and Skin Reactivity

    J. Exper. Med

    (1963)
  • M. Shito

    Non-specific Resistance to Infections

    Ann. Rev. Microbiol

    (1959)
  • I.L. Bennett et al.

    Bacterial Pyrogens

    Pharmacol. Rev

    (1957)
  • Cited by (0)

    Aided by grants from the United States Public Health Service (AI-00798 and HE-2085). National Foundation, and the American Heart Association.

    Established Investigator, American Heart Association.

    ∗∗

    American Legion Memorial Heart Research Professor of Pediatrics.

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