eLetters

231 e-Letters

  • High-dose of Fluticasone propionate in mild asthmatics
    S K Agarwal

    Dear Editor

    In a study [1] by Ward et al the dose of fluticasone propionate used for mild asthmatics was several folds higher (1500 mcg) whereas the recommended dose in different International guidelines is only 200 mcg.The other flaws which need clarification are:
    a) Inhaled corticosteroid was withdrawn 3 months before putting the patients on this study; there is no mention of the number of puffs o...

    Show More
  • COPD outcomes in ICU
    Luke S Howard

    Dear Editor

    The data presented by Breen et al[1] regarding the outcomes of patients with COPD are encouraging and lend support to the respiratory physician often faced with nihilistic attitudes towards ventilating these patients in acute respiratory failure. However, despite the proposition by the authors that certain patients with likely poor outcomes might have been excluded, the ICU stays for both gr...

    Show More
  • ETS and asthma: U shaped effect? - Author's response
    Dear Editor

    Dr McFadden is putting forward an interpretation of the small non- significant decrease in asthma episode contacts seen amongst those with moderate exposure to passive smoking. In our view this is unwise. The effect could well be due simply to the play of chance. Further we have shown that non-clinical factors have a dominant influence on visit frequency and that the frequency of contacts is a poor measu...

    Show More
  • Obesity is associated with respiratory problems, not necessarily asthma - Author's response
    Dear Editor,

    We fully appreciate Dr Furness's comments on the limitations of the definition of asthma based on parents' reports of symptoms and we have contributed on the subject.[1] Epidemiological studies of asthma have to rely on reported symptoms,[2][3] but a better understanding of what parents call wheeze would be of great importance, especially in a multicultural society. The validity of reported asthma symptoms...

    Show More
  • Intravenous IL-5 antagonist in bronchial asthma
    Dear Editor,

    Intravenous interleukin-5 antagonist has great potential and studies have shown that it may be beneficial in chronic asthmatics for 3 to 6 months.

    Now the understanding of cytokines and their beneficial and harmful effects are well known but still cure of bronchial asthma appears to be a remote possibility. Non-compliance in patients is very high and once they feel better they take medicines irre...

    Show More
  • Statistical error or not?
    Dear Editor,

    I read with great interest the article of Nakayama et al about tuberculin responses and risk of pneumonia in immobile elderly patients. It is known that TH1 cells are important in delayed type hypersensitivity responses to tuberculin. The authors' findings are important in assessment of pathogenesis of pneumonia in elderly patients. But I have some doubts about the analysis of data. The groups were compared...

    Show More
  • Obesity is associated with respiratory problems, not necessarily asthma
    Dear Editor,

    I was interested to see the work of Figueroa-Munoz and colleagues showing an association between obesity and wheeze.[1] I would like to caution against their conclusion. In their study asthma is defined according to "asthma attack" and parental reports of wheeze. Several studies have shown parental reporting of wheeze to be unreliable.[2][3][4]

    Please can the authors clarify who defined, "asthma att...

    Show More
  • Lower respiratory tract infection and antibiotics
    Dear Editor

    The observational data presented by Macfarlane et al on the aetiology of acute lower respiratory tract illness in the community[1] confirm that the often stated assertion that these illnesses are usually caused by viral infection is incorrect. The high prevalence of bacteriological and atypical pathogens, and in particular the high prevalence of C pneumoniae in these patients is of interest and points to the n...

    Show More
  • ETS and asthma: U shaped effect?
    Dear Editor,

    If the abstract indicates correctly that children of totally non-smoking parents were not included in the study, I see that as a significant weakness.

    The study found, as might be expected by many, an increase in contacts for asthma episodes among children most heavily exposed to environmental tobacco smoke (ETS).

    However, it also found a non-significant but noteworthy decrease in asthma epi...

    Show More
  • CAP deaths, observations from the community
    Dear Editor,

    I read with interest this article in Thorax and have been worried by the comments in "Pulse" which followed (9 December 2000).

    The lack of information about the general practitioner (GP) consultations, and the non- availability of records is alarming and dispiriting. Particularly when nowadays much information is computerised and records can in emergency situations, given the hard work of Health...

    Show More

Pages