eLetters

176 e-Letters

published between 2002 and 2005

  • Authors' reply to Koh and Kwon
    Robert Wilson

    Dear Editor,

    We would agree with much of the content of the interesting letter from Doctors Koh and Kwon, particularly the details of M.avium complex infection and the use of CT scans in making the diagnosis.[1] We have also had experience of bronchoscopy and biopsy being necessary to make the diagnosis in some cases with suggestive radiology. The one point on which we disagree is the value of routine annual scr...

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  • Consideration of Palivizumab not justified
    Rollo D Clifford

    Dear Editor,

    Broughton and colleagues state that consideration should be given to use of prophylactic palivizumab to infants born at less than 32 weeks in the case of maternal smoking or even if they have siblings. The authors however present no data from their own or other studies to indicate that this would be in any way cost effective or justified. Certainly the word "consider" is fortunate given the stated fu...

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  • Bronchiectasis and nontuberculous mycobacterial pulmonary infection
    Won-Jung Koh

    Dear Editor,

    We read with great interest the paper by Wickremasinghe et al. on the prevalence of nontuberculous mycobacteria (NTM) in patients with bronchiectasis.[1] They showed that the prevalence of NTM was uncommon (only 2%) both in 50 newly referred patients and 50 follow up patients. However, the authors stated in the Discussion that it is now our practice to screen our patients routinely once a year bec...

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  • Predicting in-hospital death related to pulmonary embolism
    Andrew RL Medford

    Dear Editor,

    Ghuysen et al in their recent retrospective study demonstrated the potential value of CTPA RV/LV ratio in predicting in-hospital mortality related to pulmonary embolism.[1] I wondered if they assessed ECG evidence of acute right heart strain and/or serum cardiac biomarkers of injury in the same study and what the relative prognostic value of these indices versus the CTPA RV/LV ratio was, assuming th...

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  • Highlighting the role of lung volume reduction surgery in COPD
    Omer Ashraf

    Dear Editor

    I read with interest this article by Sharafkhaneh et al. wherein the role of lung volume reduction surgery (LVRS) in improving expiratory flow limitation by decreasing thoracic gas compression, is indicated

    Apart from the obvious benefits for emphysema patients shown in this report, it is important to highlight the other significant beneficial roles of LVRS. The procedure is now considered as...

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  • Study design and interpretation
    Imran Aziz

    Dear Editor

    The study by Duffy et al,(1) published in the September issue of Thorax, has a number of errors in the design and interpretation of the results.

    In the study design; 1- By definition COPD is a condition where FEV1 changes very little, so a study of COPD intervention based on change in FEV1 is not correct. 2- The study was in theory powered to show what amounts to about 30% improvement in FEV1...

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  • The potential effect of dichotomising age (a continuous variable) in multivariate model analysis
    Abebaw M Yohannes

    Dear Editor

    We have read with great interest, Soler-Catauna and colleagues [1] article that examined, in an impressive prospective study with five years follow-up, factors predicting poor prognosis and mortality in patients with severe acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Their findings are complimentary with the current available literature in identifying that older age, arteri...

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  • LTBI, hepatotoxicity and the anti TNF patient
    Dean D Creer

    Dear Editor

    We read with interest the letter by Provenzano et al (1) on TB screening and anti-TNF treatment and wish to comment on this highly topical subject.

    Latent TB infection (LTBI) was diagnosed in 24.6% of the 69 rheumatological patients undergoing evaluation for anti-TNF treatment (n=17) of which 6 received anti-TNF therapy and TB chemoprophylaxis. The ethnicity and place of birth was not commen...

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  • Inhaled steroids Protect Heart in COPD Patients
    Samaria J.K.

    Dear Editor

    Chronic obstructive pulmonary disease and other disorders, associated with reduced lung function, are strong risk factors for cardiovascular events, independent of smoking. In general, for every 10% decrease in FEV1, all-cause mortality increases by 14%, cardiovascular mortality increases by 28%1. Patients with chronic obstructive pulmonary disease (COPD) are predisposed to atherosclerosis and coronary...

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  • Excluding LIP is essential before attributing a diagnosis of immune reconstitution inflammatory synd
    Daniel Richardson

    Dear Editor

    We thank Dr Singh for his/her comments on our case report.[1] We agree that LIP is an important differential diagnosis in this case and is associated with pulmonary nodules and pulmonary cysts, although they are usually perivascular.[1-3] Firstly we acknowledge an erratum in the text which was edited and submitted without re-review by the contributing pathologist (AR). Specifically there were numero...

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