Article Text

PDF
Images in Thorax
Aortic rupture involving matrix metalloproteinases 8 and 9 during Staphylococcus aureus pneumonia
  1. Mitsuo Hashimoto1,
  2. Saki Kuriiwa1,
  3. Ayako Kojima1,
  4. Shunsuke Minagawa1,
  5. Takanori Numata1,
  6. Hiromichi Hara1,
  7. Jun Araya1,
  8. Yumi Kaneko1,
  9. Katsutoshi Nakayama1,
  10. Mamiko Owada2,
  11. Daisuke Aizawa2,
  12. Takashi Yorozu2,
  13. Masafumi Suzuki2,
  14. Kazuyoshi Kuwano1
  1. 1Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan
  2. 2Department of Pathology, The Jikei University School of Medicine, Tokyo, Japan
  1. Correspondence to Dr Mitsuo Hashimoto, Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan ; mitsuoha-georgetown{at}live.jp

Statistics from Altmetric.com

An 87-year-old man was admitted to Jikei University Hospital presenting with fever and fatigue. Physical examinations revealed inspiratory coarse crackles on the left lung field. A chest CT detected a tumour-like consolidation around the thoracic aorta (figure 1A). Biochemical examinations found a high number of white blood cells and elevated C-reactive protein level, and a diagnosis of pneumonia was made. Penicillin antibiotics (ampicillin/sulbactam) were administered. Two days later, methicillin-sensitive Staphylococcus aureus (MSSA) was detected in two sets of blood cultures. An echocardiogram showed no vegetation and a urine culture was negative. A sputum culture was unobtainable, but pneumonia was the only focus of infection for the MSSA. Penicillin antibiotics were continued, but the patient suddenly developed cardiopulmonary arrest …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.