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A randomised controlled trial of CPAP versus non-invasive ventilation for initial treatment of obesity hypoventilation syndrome
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  • Published on:
    Response to: A randomised controlled trial of CPAP vs non-invasive ventilation for initial treatment of obesity hypoventilation syndrome
    • Mark E Howard, Respiratory Physician
    • Other Contributors:
      • Amanda J Piper, Bronwyn Stevens, Anne E Holland, Brendon J Yee, Eli Dabscheck, Duncan Mortimer, Angela T Burge, Daniel Flunt, Catherine Buchan, Linda Rautela, Nicole Sheers, David Hillman & David J Berlowitz

    Dear Editor, We thank Dr Mansell for her comments regarding our recently published trial. [1] We agree that there are different phenotypic variations within the obesity hypoventilation syndrome (OHS), although it remains to be determined whether OHS with co-existent obstructive sleep apnoea (OSA) responds differently to treatment in comparison to OHS without OSA. [2] Acknowledging that the presence and severity of OSA in...

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    Conflict of Interest:
    None declared.
  • Published on:
    Comment on: A randomised controlled trial of CPAP versus non-invasive ventilation for initial treatment of obesity hypoventilation syndrome
    Dear Editor,

    We read with great interest the article by Howard et al[1] and commend the authors on this excellent piece of work. However, we wish to raise several points for consideration of this work in a clinical context. Firstly, it is not clear whether the patients being treated were truly patients with obesity hypoventilation failure (OHS) or whether in fact they had hypercapnic obstructive sleep apnoea (OSA). There is in...

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    Conflict of Interest:
    None declared.