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Seasonal variation in incidence of sarcoidosis: a population-based study, 1976–2013
  1. Patompong Ungprasert1,
  2. Cynthia S Crowson1,2,
  3. Eric L Matteson1,3
  1. 1Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
  2. 2Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, Rochester, Minnesota, USA
  3. 3Division of Epidemiology, Department of Health Science Research, Mayo Clinic, Rochester, Minnesota, USA
  1. Correspondence to Dr Patompong Ungprasert, Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, 200 First avenue SW, Rochester, MN 55905, USA; P.Ungprasert{at}gmail.com, Ungprasert.Patompong{at}mayo.edu

Abstract

Studies of seasonal patterns of incidence of sarcoidosis may provide a better understanding of potential environmental triggers of the disease. In this study, Olmsted County, Minnesota residents who were diagnosed with sarcoidosis between 1976 and 2013 were identified based on individual medical record review. The seasonal variation of incident sarcoidosis was then calculated. The age-adjusted and sex-adjusted incidence rate of sarcoidosis was lower in autumn (2.0/100 000; 95% CI 1.5 to 2.5) compared with winter (3.2/100 000; 95% CI 2.6 to 3.8), spring (2.8/100 000; 95% CI 2.2 to 3.4) and summer (2.9/100 000; 95% CI 2.2 to 3.5, p=0.024). Subgroup analysis per decade consistently showed lower incidence of sarcoidosis in autumn.

  • Sarcoidosis
  • Clinical Epidemiology

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