You are here

  • Home
  • Archive
  • Volume 71, Issue 5
  • Prolonged controlled mechanical ventilation in humans triggers myofibrillar contractile dysfunction and myofilament protein loss in the diaphragm

Article info

Article menu

Download PDFPDF

Respiratory research
Original article
Prolonged controlled mechanical ventilation in humans triggers myofibrillar contractile dysfunction and myofilament protein loss in the diaphragm
Free

Authors

  • Sabah N A Hussain Meakins-Christie Laboratories and Critical Care Division, McGill University, Montréal, Québec, Canada Department of Critical Care, McGill University Health Centre Research Institute, Montréal, Québec, Canada Meakins-Christie Laboratories and Respiratory Division, McGill University, and Program for Translational Research in Respiratory Diseases, McGill University Health Centre Research Institute, Montréal, Québec, Canada PubMed articlesGoogle scholar articles
  • Anabelle S Cornachione Department of Pathology, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, Brazil PubMed articlesGoogle scholar articles
  • Céline Guichon Meakins-Christie Laboratories and Critical Care Division, McGill University, Montréal, Québec, Canada PubMed articlesGoogle scholar articles
  • Auday Al Khunaizi Meakins-Christie Laboratories and Critical Care Division, McGill University, Montréal, Québec, Canada PubMed articlesGoogle scholar articles
  • Felipe de Souza Leite Department of Kinesiology, McGill University, Montréal, Québec, Canada PubMed articlesGoogle scholar articles
  • Basil J Petrof Meakins-Christie Laboratories and Respiratory Division, McGill University, and Program for Translational Research in Respiratory Diseases, McGill University Health Centre Research Institute, Montréal, Québec, Canada PubMed articlesGoogle scholar articles
  • Mahroo Mofarrahi Meakins-Christie Laboratories and Critical Care Division, McGill University, Montréal, Québec, Canada PubMed articlesGoogle scholar articles
  • Nikolay Moroz Meakins-Christie Laboratories and Critical Care Division, McGill University, Montréal, Québec, Canada PubMed articlesGoogle scholar articles
  • Benoit de Varennes Division of Cardiac Surgery, Department of Surgery, Faculty of Medicine, McGill University, Montréal, Québec, Canada PubMed articlesGoogle scholar articles
  • Peter Goldberg Meakins-Christie Laboratories and Critical Care Division, McGill University, Montréal, Québec, Canada Meakins-Christie Laboratories and Respiratory Division, McGill University, and Program for Translational Research in Respiratory Diseases, McGill University Health Centre Research Institute, Montréal, Québec, Canada PubMed articlesGoogle scholar articles
  • Dilson E Rassier Departments of Kinesiology and Physical Education, Physiology and Physics, McGill University, Montreal, Quebec, Canada PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Dilson Rassier, Department of Kinesiology, McGill University, 475 Pine Ave West, Montréal, Québec, Canada H2W 1S4; dilson.rassier{at}mcgill.ca
View Full Text

Citation

Hussain SNA, Cornachione AS, Guichon C, et al
Prolonged controlled mechanical ventilation in humans triggers myofibrillar contractile dysfunction and myofilament protein loss in the diaphragm
Thorax 2016;71:436-445.

Publication history

  • Received July 10, 2015
  • Revised January 5, 2016
  • Accepted January 6, 2016
  • First published March 31, 2016.
Online issue publication 
December 20, 2023

Article Versions

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Copyright information

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/