In this study, the data for 2633 participants from the Framingham Heart Study were analysed to explore any association between a polymorphism in the promoter of a mucin gene (MUC5B) and radiological evidence of interstitial lung abnormalities.

Data for participants were evaluated to include physical examination findings, respiratory questionnaires, spirometry including diffusion capacity for carbon monoxide, genotyping for MUC5B and thoracic …