rss
Thorax doi:10.1136/thoraxjnl-2013-203254
  • Chest clinic
  • Audit, research and guideline update

Migration and tuberculosis in the UK: targeting screening for latent infection to those at greatest risk of disease

  1. Marc Lipman4
  1. 1Tuberculosis Section, Public Health England, London, UK
  2. 2Centre for Lysosomal and Metabolic Diseases, Sophia Children's Hospital, Erasmus MC University Medical Centre, Rotterdam, The Netherlands
  3. 3Research Department for Infections and Population Health, University College London, London, UK
  4. 4Centre for Respiratory Medicine, Royal Free London NHS Foundation Trust, University College London, London, UK
  1. Correspondence to Dr M E Kruijshaar, Centre for Lysosomal and Metabolic Diseases, Sophia Children's Hospital, Erasmus MC University Medical Centre, Dr Molenwaterplein 60, Rotterdam 3000 CB, The Netherlands; m.kruijshaar{at}erasmusmc.nl
  • Received 12 January 2013
  • Revised 29 May 2013
  • Accepted 6 June 2013
  • Published Online First 4 July 2013

Abstract

Active tuberculosis (TB) in the UK predominantly affects the non-UK born, but is generally not manifest at the time of UK entry. Strategies to detect latent TB infection (LTBI) in this population are, therefore, important. To date, targeted screening has focused on TB risk estimates based on the incidence in the country of origin. Using TB incidence in the UK and migration data, we estimated the numbers needed to be tested and treated for LTBI to prevent one case of TB disease. Numbers were the lowest in Somalian and the highest in South African and Filipino migrants, which contrasts with TB rates in these countries. Targeting screening on the basis of incidence in the UK may thus improve effectiveness.


Free sample
This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of Thorax.
View free sample issue >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Navigate This Article