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The OSCAR trial randomised acute respiratory distress syndrome (ARDS) patients to either high frequency oscillatory ventilation (HFOV) or conventional ventilatory support. This UK multicentre study recruited 795 patients between 2007 and 2012 who met established diagnostic criteria for ARDS and were expected to require ventilation for at least 2 days. Those with prior prolonged mechanical ventilation (>7 days), obstructive …
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