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Correspondence
Thorax editorial by Jenkins and Beasley related to tiotropium respimat
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  1. Norbert Metzdorf,
  2. Christoph Hallmann,
  3. Bernd Disse
  1. Department of Clinical Development & Medical Affairs, Boehringer Ingelheim Pharma GmbH & Co KG, Ingelheim, Germany
  1. Correspondence to Dr Norbert Metzdorf, Department of Clinical Development & Medical Affairs, Boehringer Ingelheim Pharma GmbH & Co KG, Binger Strasse 173, Ingelheim 55216, Germany; norbert.metzdorf{at}boehringer-ingelheim.com

https://doi.org/10.1136/thoraxjnl-2013-203228

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    We thank Drs Jenkins and Beasley for their comments in the recent editorial regarding tiotropium (SPIRIVA).1 Preceding the Singh et al 2 analysis cited by the authors, Boehringer Ingelheim (BI) had analysed both the tiotropium HandiHaler and Respimat pooled datasets using patient-level data on-treatment as well as including vital status. The results showed a nominally statistically significant reduction for tiotropium HandiHaler and a numerical increase with tiotropium Respimat compared with the respective placebo group for all-cause mortality.

    These results are adequately reflected in the local SPIRIVA product information (http://www.medicines.org.uk/EMC/searchresults.aspx?term=spiriva&searchtype=QuickSearch) …

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