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Thorax doi:10.1136/thoraxjnl-2012-202122
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Lung-protective mechanical ventilation may be associated with a long-term survival benefit for patients with acute lung injury

  1. Toni Bryant
  1. Correspondence to Dr Toni Bryant, CT1, Queen Elizabeth Hospital Birmingham, Mindelsohn Way, Birmingham B15 2WB, UK; tonibryant{at}nhs.net

Volume and pressure-limited (‘lung-protective’) mechanical ventilation decreases short-term mortality in patients with acute lung injury (ALI). This multicentre prospective cohort study from the USA evaluated the association of lung-protective mechanical ventilation with a 2-year survival period in patients with ALI.

The study included 485 mechanically ventilated patients with ALI diagnosed according to the American-European Consensus criteria. After onset of ALI, …


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