Host genotype-specific therapies for tuberculosis
- Correspondence to Dr Joanna Devlin, CT2, Royal Hampshire County Hospital, Romsey Road, Winchester, Hampshire SO22 5DG, UK; joannadevlin{at}doctors.org.uk
This paper suggests that therapies for tuberculosis (TB) will, in the future, be tuned specifically to the patient's genotype. Using zebra fish and human models, Tobin et al demonstrated that susceptibility to TB can be caused by both reduced and increased inflammatory activity, which in turn is governed by the patient's …
