Bronchoalveolar lavage-directed therapy does not affect prevalence of Pseudomonas aeruginosa infection and structural lung injury in children with cystic fibrosis
- Correspondence to Dr Helmy Haja Mydin, Department of Respiratory Medicine, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK; enidan{at}doctors.org.uk
Early Pseudomonas aeruginosa pulmonary infections lead to increased morbidity and mortality in children with cystic fibrosis (CF). As this diagnosis is difficult to ascertain in the non-expectorating patient, the authors set out to determine if bronchoalveolar lavage (BAL)-directed therapy during the first 5 years of life leads to better outcomes than standard practice (which is therapy based …
