Article Text

other Versions

  • You are currently viewing an earlier version of this article (September 27, 2007).

PDF

Assessing the Impact of Pulmonary Rehabilitation on Functional Status in Chronic Obstructive Pulmonary Disease
  1. Louis Laviolette (louis.laviolette{at}crhl.ulaval.ca)
  1. Centre de Recherche, Hôpital Laval, Institut universitaire de cardiologie et de pneumologie de l’Uni, Canada
    1. Jean Bourbeau (jean.bourbeau{at}mcgill.ca)
    1. Respiratory, Epidemiology and Clinical Research Unit, Montreal Chest Institute of the Royal Victoria, Canada
      1. Sarah Bernard (sarah.bernard{at}crhl.ulaval.ca)
      1. Centre de Recherche, Hôpital Laval, Institut universitaire de cardiologie et de pneumologie de l’Uni, Canada
        1. Yves Lacasse (yves.lacasse{at}crhl.ulaval.ca)
        1. Centre de Recherche, Hôpital Laval, Institut universitaire de cardiologie et de pneumologie de l’Uni, Canada
          1. Véronique Pepin (v-pepin{at}crhsc.rtss.qc.ca)
          1. Centre de recherche, Hôpital du Sacré-Coeur de Montréal, Canada
            1. Marie-Josée Breton (marie-josee.breton{at}crhl.ulaval.ca)
            1. Centre de Recherche, Hôpital Laval, Institut universitaire de cardiologie et de pneumologie de l’Uni, Canada
              1. Marc Baltzan (marc.baltzan{at}clinepi.mcgill.ca)
              1. Centre Hospitalier Mont-Sinaï, Canada
                1. Michel Rouleau (rouleaum{at}globetrotter.net)
                1. Centre Hospitalier Affilié Enfant-Jésus, Canada
                  1. François Maltais (francois.maltais{at}med.ulaval.ca)
                  1. Centre de Recherche, Hôpital Laval, Institut universitaire de cardiologie et de pneumologie de l’Uni, Canada

                    Abstract

                    Rationale - The optimal way of assessing the impact of pulmonary rehabilitation on functional status in chronic obstructive pulmonary disease (COPD) is currently unknown. The minimal clinically important difference for the constant workrate cycling exercise also needs to be investigated to facilitate its interpretation.

                    Objective – Evaluate the changes in the 6-minute walking test and in the constant workrate cycle endurance test immediately following and 1-year after pulmonary rehabilitation, along with the importance of these changes in term of health status in patients with COPD.

                    Methods - Patients with COPD (age: 65  8 years, mean  SD; FEV1: 45  15 % predicted) were recruited from a multicenter prospective cohort study and were evaluated at baseline, immediately after a pulmonary rehabilitation program (n=157) and at 1 year (n=106). The 6-min walking test and the cycle endurance test were performed at each evaluation. Health status was evaluated with the St. Georges Respiratory Questionnaire.

                    Measurements and Main Results - Following pulmonary rehabilitation, cycle endurance time increased (198  352s, p<0.0001) and stayed over baseline values at 1 year (p<0.0001). The 6-minute walking distance also showed improvements following rehabilitation (25  52m, p<0.0001) but returned to baseline values at the 1 year follow-up. Changes in cycle endurance time were more closely associated with changes in health status than those of the 6-min walking test. A 100-200s improvement in the cycle endurance time was associated with clinically meaningful changes in the St. Georges Respiratory Questionnaire scores.

                    conclusions - The cycle endurance test was more responsive that the 6-min walking test to detect improvement in exercise tolerance following pulmonary rehabilitation and was also better correlated with improvements in health status. An improvement in the cycle endurance time ranging from 100-200s appeared to be clinically meaningful.

                    • Cycle Endurance Test
                    • Exercise Test
                    • Health Status
                    • Pulmonary Disease, Chronic Obstructive
                    • Pulmonary Rehabilitation

                    Statistics from Altmetric.com

                    Request permissions

                    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.