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Mechanisms by which obesity impacts upon asthma
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  • Published on:
    Response to correspondence from Professor Lipworth

    We thank Professors Lipworth and Anderson for their very thoughtful comments in their response to our piece1, and for pointing out clear strategies for treating obesity-associated asthma without expensive therapies, e.g., with improved delivery of inhaled corticosteroids and/or weight reduction.

    It should be noted however, that the focus of the piece was on mechanisms by which obesity might cause asthma,...

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    Conflict of Interest:
    None declared.
  • Published on:
    Obesity and asthma - do we need expensive therapies?
    • Brian J Lipworth, Professor of Allergy & Pulmonology
    • Other Contributors:
      • Dr William J Anderson

    We read with interest the state of the art review by Umetsu on mechanisms by which obesity impacts asthma [1]. He has clearly outlined the extent to which molecular targets, both within allergic (T-helper 2 [TH2]) and non-allergic mechanistic pathways of asthma, need further evaluation and drug development for obese asthmatics. This was on the basis that current standard therapies for asthma such as inhaled corticoste...

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    Conflict of Interest:
    None declared.