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Summary of recommendations
Principles of mechanical ventilation
Modes of mechanical ventilation
Recommendation
1. Pressure-targeted ventilators are the devices of choice for acute NIV (Grade B).
Good practice points
Both pressure support (PS) and pressure control modes are effective.
Only ventilators designed specifically to deliver NIV should be used.
Choice of interface for NIV
Recommendation
2. A full face mask (FFM) should usually be the first type of interface used (Grade D).
Good practice points
A range of masks and sizes is required and staff involved in delivering NIV need training in and experience of using them.
NIV circuits must allow adequate clearance of exhaled air through an exhalation valve or an integral exhalation port on the mask.
Indications for and contra-indications to NIV in AHRF
Recommendation
3. The presence of adverse features increase the risk of NIV failure and should prompt consideration of placement in high dependency unit (HDU)/intensive care unit (ICU) (Grade C).
Good practice points
Adverse features should not, on their own, lead to withholding a trial of NIV.
The presence of relative contra-indications necessitates a higher level of supervision, consideration of placement in HDU/ICU and an early appraisal of whether to continue NIV or to convert to invasive mechanical ventilation (IMV).
Monitoring during NIV
Good practice points
Oxygen saturation should be continuously monitored.
Intermittent measurement of pCO2 and pH is required.
ECG monitoring is advised if the patient has a pulse rate >120 bpm or if there is dysrhythmia or possible cardiomyopathy.
Supplemental oxygen therapy with NIV
Recommendations
4. Oxygen enrichment should be adjusted to achieve SaO2 88–92% in all causes of acute hypercapnic respiratory failure (AHRF) treated by NIV (Grade A).
5. Oxygen should be entrained as close to the patient as possible (Grade C).
Good practice points
As gas exchange will improve with increased alveolar ventilation, NIV settings should be optimised before increasing the FiO2.
The flow rate of supplemental oxygen may need to be increased when ventilatory pressure is increased to maintain the same SaO2 …
Supplementary materials
Supplementary Data
This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.
- Data supplement 1 - Online appendix 1
- Data supplement 2 - Online appendix 2
- Data supplement 3 - Online appendix 3