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S4 Relationship Between Historic Uk Asbestos Imports And Annual Mortality Due To Mesothelioma, Asbestosis And Idiopathic Pulmonary Fibrosis
  1. CM Barber,
  2. RE Wiggans,
  3. D Fishwick
  1. Centre for Workplace Health, Health and Safety Laboratory, Buxton, UK

Abstract

Background Previous studies from a number of countries have demonstrated that the rising mortality due to mesothelioma and asbestosis can be predicted from their historic asbestos usage. Mortality due to idiopathic pulmonary fibrosis (IPF) is also rising in the UK, without any identified explanation. This analysis compared annual male and female mortality due to IPF, asbestosis and mesothelioma, and examined the relationship between mortality and national asbestos import data.

Methods Mortality data for IPF and asbestosis in England and Wales were available from the Office for National Statistics (ONS). Data for mesothelioma deaths in England and Wales and historic UK asbestos import data were available from the Health and Safety Executive (HSE). The numbers of annual deaths due to each condition were plotted separately by gender, against UK asbestos imports 48 years earlier. Pearson correlation co-efficients were then calculated.

Results Correlation co-fficients for each condition are shown in Table 1. The annual number of deaths due to mesothelioma and IPF were significantly correlated with historical asbestos imports for both genders. For asbestosis mortality, a similar relationship was found for male but not female deaths.

Conclusion The strength of the association between IPF and historical asbestos imports was similar to that seen for mesothelioma mortality. This finding suggests that the role of occupational and environmental asbestos exposure in the aetiology of IPF requires further consideration.

Abstract S4 Table 1

Correlation co-efficients for historic national asbestos import data, plotted against annual mortality due to mesothelioma, asbestosis, and idiopathic pulmonary fibrosis (IPF)

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