Measuring respiratory symptoms in clinical trials of COPD: reliability and validity of a daily diary

N K Leidy; C C Sexton; P W Jones; S M Notte; B U Monz; L Nelsen; M Goldman; L T Murray; S Sethi

doi:10.1136/thoraxjnl-2013-204428

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Chronic obstructive pulmonary disease

Original article

Measuring respiratory symptoms in clinical trials of COPD: reliability and validity of a daily diary

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	Abstract	Full	Pdf
Mar 2014	654	460	240
Apr 2014	1332	212	237
May 2014	836	116	170
Jun 2014	292	78	81
Jul 2014	149	65	66
Aug 2014	132	68	40
Sep 2014	132	52	64
Oct 2014	107	46	57
Nov 2014	74	67	79
Dec 2014	42	29	48
Jan 2015	55	76	174
Feb 2015	34	52	216
Mar 2015	86	66	137
Apr 2015	47	39	102
May 2015	47	35	88
Jun 2015	21	42	87
Jul 2015	20	44	48
Aug 2015	31	35	46
Sep 2015	52	55	42
Oct 2015	19	27	24
Nov 2015	38	40	64
Dec 2015	17	38	36
Jan 2016	18	44	55
Feb 2016	17	33	43
Mar 2016	27	30	67
Apr 2016	23	39	75
May 2016	27	36	59
Jun 2016	23	29	54
Jul 2016	14	27	47
Aug 2016	24	17	49
Sep 2016	18	32	43
Oct 2016	48	50	40
Nov 2016	36	53	41
Dec 2016	23	27	29
Jan 2017	22	22	55
Feb 2017	13	17	30
Mar 2017	0	31	32
Apr 2017	1	41	26
May 2017	1	41	36
Jun 2017	6	19	39
Jul 2017	47	44	78
Aug 2017	32	25	74
Sep 2017	48	37	75
Oct 2017	52	34	39
Nov 2017	52	40	50
Dec 2017	54	40	36
Jan 2018	50	36	25
Feb 2018	54	39	27
Mar 2018	52	40	32
Apr 2018	80	70	42
May 2018	52	45	35
Jun 2018	37	25	21
Jul 2018	41	29	28
Aug 2018	39	25	29
Sep 2018	31	21	26
Oct 2018	50	38	35
Nov 2018	39	34	27
Dec 2018	43	35	32
Jan 2019	52	32	28
Feb 2019	35	25	26
Mar 2019	38	26	38
Apr 2019	43	29	29
May 2019	47	43	30
Jun 2019	39	35	29
Jul 2019	46	32	27
Aug 2019	35	29	26
Sep 2019	25	15	17
Oct 2019	77	45	37
Nov 2019	48	26	22
Dec 2019	43	19	13
Jan 2020	27	21	16
Feb 2020	37	31	29
Mar 2020	47	23	28
Apr 2020	30	18	22
May 2020	35	25	24
Jun 2020	23	23	10
Jul 2020	34	16	16
Aug 2020	50	40	31
Sep 2020	80	56	30
Oct 2020	58	46	21
Nov 2020	36	28	24
Dec 2020	37	33	20
Jan 2021	45	36	22
Feb 2021	46	34	28
Mar 2021	53	37	25
Apr 2021	37	23	12
May 2021	33	25	11
Jun 2021	18	18	9
Jul 2021	17	17	10
Aug 2021	18	18	19
Sep 2021	28	28	22
Oct 2021	39	28	26
Nov 2021	45	23	36
Dec 2021	62	45	20
Jan 2022	47	26	20
Feb 2022	47	37	21
Mar 2022	36	37	15
Apr 2022	48	41	25
May 2022	52	48	26
Jun 2022	52	42	14
Jul 2022	41	27	9
Aug 2022	49	35	8
Sep 2022	26	28	14
Oct 2022	55	51	11
Nov 2022	38	26	13
Dec 2022	18	14	14
Jan 2023	39	19	16
Feb 2023	50	44	13
Mar 2023	57	47	14
Apr 2023	20	14	16
May 2023	73	44	29
Jun 2023	52	40	11
Jul 2023	36	28	16
Aug 2023	48	24	15
Sep 2023	63	47	19
Oct 2023	46	24	10
Nov 2023	38	22	9
Dec 2023	62	40	16
Jan 2024	37	36	33
Feb 2024	45	25	35
Mar 2024	59	38	106
Total	8108	4939	5058

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