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Correspondence
Response to: Domiciliary long term non-invasive ventilation in COPD: should we select subgroups with a better likelihood to respond to NIV in subsequent randomised controlled trials?
  1. F M Struik1,2,
  2. P J Wijkstra1,2
  1. 1 Department of Pulmonology/Center for Home Mechanical Ventilation, University of Groningen, University Medical Center Groningen (UMCG), Groningen, The Netherlands
  2. 2 Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen (UMCG), Groningen, The Netherlands
  1. Correspondence to F M Struik, Department of Pulmonary Diseases/Home Mechanical Ventilation, University Medical Center Groningen, Triade gebouw AA62, Groningen 9713 GZ, The Netherlands; f.m.struik{at}umcg.nl

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Dear editor,

We thank Borel et al 1 for their comments on our paper.2 Borel and colleagues suggest that future studies should focus on specific COPD subgroups who have better likelihood of response to chronic non-invasive ventilation (NIV). They recently showed that obese COPD patients respond better to NIV compared with non-obese patients.3 We completely agree with their suggestion about focusing on COPD subgroups for future studies and in fact we tried to do so as well. In our study, we investigated the benefits of chronic NIV in COPD patients after they received ventilatory support due to acute respiratory failure. However, we focused on a more specific COPD group (in the …

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