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Pulmonary vascular volumes and airways obstruction in SCD patients
  1. Anne Greenough1,2,
  2. Alan Lunt1,2
  1. 1 Division of Asthma, Allergy and Lung Biology, MRC-Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, UK
  2. 2 NIHR Biomedical Research Centre at Guy's and St Thomas’ NHS Foundation Trust and King's College London, London, UK
  1. Correspondence to Professor Anne Greenough, NICU, 4th Floor Golden Jubilee Wing, King's College Hospital, Denmark Hill, London SE5 9RS, UK; anne.greenough{at}

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Dear Editor

We read with interest the recent paper by Chaudry et al 1 in which the authors describe an obstructive ventilatory defect in children with sickle cell disease (SCD) which was not linked to bronchial hyper-responsiveness, as assessed by methacholine challenge testing, or to eosinophillic inflammation. Their results further demonstrate that the airflow obstruction …

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