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Positional oximetry to screen for pulmonary arteriovenous malformations in HHT
  1. Susan Carpenter1,
  2. Janina Josepovici1,
  3. Giuseppe Latino1,
  4. Felix Ratjen1,2,3
  1. 1Division of Respiratory Medicine, Department of Paediatrics, The Hospital for Sick Children, Toronto, Canada
  2. 2Physiology & Experimental Medicine, Research Institute, The Hospital for Sick Children, Toronto, Canada
  3. 3University of Toronto, Toronto, Canada
  1. Correspondence to Professor Felix Ratjen, Division of Respiratory Medicine, Department of Paediatrics, Rm. 4534, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8; felix.ratjen{at}sickkids.ca

Abstract

Orthodeoxia has been described in patients with hereditary haemorrhagic telangiectasia (HHT) and pulmonary arteriovenous malformations (PAVM), but its usefulness in screening children for PAVMs is unknown. We show here that while oximetry is overall lower in children with significant PAVMs, supine and upright oximetry is of no additional diagnostic value indicating that positional oximetry is not a useful screening test for PAVMs.

  • Rare lung diseases

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