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Correspondence
Efficacy of lower-limb muscle training modalities in severely dyspnoeic individuals with COPD and quadriceps muscle weakness: response from the authors
  1. Maurice J H Sillen1,
  2. Frits M E Franssen1,
  3. Jeannet M L Delbressine1,
  4. Anouk W Vaes1,
  5. Emiel F M Wouters1,2,
  6. Martijn A Spruit1
  1. 1 Department of Research & Education, CIRO+, Centre of expertise for chronic organ failure, Horn, The Netherlands
  2. 2 Department of Respiratory Medicine, Maastricht University Medical Centre (MUMC+), Maastricht, The Netherlands
  1. Correspondence to Maurice Sillen, Department of Research & Education, CIRO+, Centre of expertise for chronic organ failure, Hornerheide 1, Horn 6085 NM, The Netherlands; mauricesillen{at}ciro-horn.nl

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We thank Chaplin and Latimer for their interest in the DICES study.1 The correspondents question the validity of the power calculation, and in turn, state that we cannot conclude that high-frequency neuromuscular electrical stimulation (HF-NMES) and strength training have equivalent effects in severely dyspnoeic patients with COPD and quadriceps muscle weakness at baseline.1 At the time of the start of the …

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