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ERK3 in lung cancer cell invasion
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  1. Arthee Yogendran
  1. Correspondence to Dr Arthee Yogendran, FY2, Medway NHS Foundation Trust, Department of Thoracic Medicine, Windmill Road, Gillingham ME7 5NY, UK; artheey{at}doctors.org.uk

https://doi.org/10.1136/thoraxjnl-2012-202322

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    ERK3, an atypical mitogen-activated protein kinase, was first identified 20 years ago, and its role in cancer development is yet to be fully elucidated. Steroid receptor coactivator 3 (SRC-3) has been well described in a number of different cancers, including lung cancer, as a nuclear receptor coactivator of PEA3-regulated MMP expression to promote cancer …

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