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Clinical management of patients with COPD
P267 Assessment of Cognitive Dysfunction Using the Cognitive Failures Questionnaire (CFQ) Tool in Patients with Obstructive Sleep Apnoea Syndrome (OSAS)
  1. A Dwarakanath1,
  2. D Ghosh1,
  3. S L Jamson2,
  4. M W Elliott1
  1. 1St James’ University Hospital, Leeds, Leeds, UK
  2. 2Institute for Transport Studies, University of Leeds, Leeds, UK


Introduction A wide range of cognitive deficits has been identified in patients with untreated OSAS and there has been a growing interest in the evaluation of cognitive deteriorations. The CFQ (Cognitive Failures Questionnaire) is a measure of self-reported deficits in the completion of simple everyday tasks that a person should normally be capable of completing without error and includes failures in attention, memory, perception, and motor functions. We hypothesised that patients with OSAS exhibit worse cognitive dysfunction as compared to healthy controls and this can be evaluated with the CFQ.

Methods 133 (ESS 12+/–6, ODI 31+/–24) untreated OSAS patients and 50 healthy controls (ESS 3+/–2) were invited to complete the CFQ. Patients and controls were asked how often they make various common mistakes on a 5-point Likert scale, from 0 (never) to 4 (very often). CFQ was scored by adding up the ratings for twenty-five questions, the highest possible total being one hundred, with a higher score indicating a higher incidence of cognitive failures. Comparisons were made using one way ANOVA.

Results There was a significant difference in scores between patients and the controls (26±1.6 & 38 ±1.6, P<0.0001). This difference remained significant when different severities of OSAS (mild, moderate, severe, as per ODI) were compared with controls. However there was no difference when different severities of OSAS were compared against each other (Figure 1).

Conclusion Patients with OSAS have a significant higher CFQ score compared to healthy controls. The CFQ is easy to complete and score and our data suggests it may be a useful tool for assessing cognitive dysfunction in OSAS.

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