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Thorax 67:573 doi:10.1136/thoraxjnl-2011-201328
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Cytisine improves smoking cessation

  1. Wa'el Osman
  1. Correspondence to Dr Wa'el Osman, Department of Respiratory Medicine, Dumfries and Galloway Royal Infirmary, Bankend Road, Dumfries DG1 4AP, UK; w.osman{at}nhs.net

In this single-centre, randomised, double blind, placebo-controlled trial, the efficacy and safety of cytisine as an aid in smoking cessation was compared with placebo. Three hundred and seventy participants were randomly assigned to either the active drug or placebo in an equal ratio for 25 days. Participants in both groups received a minimal amount of counselling during the study.

The primary outcome measure was sustained biochemically-verified …


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