Pulmonary mass in a 19-year-old male
- Laura-Jane E Smith1,
- David R Lawrence2,
- Irfan Kayani3,
- Arrigo Capitanio4,
- Mary Falzon4,
- Sam M Janes5,
- Neal Navani5
- 1Department of Thoracic Medicine, University College London Hospital, NHS Foundation Trust, London, UK
- 2The Heart Hospital, University College London Hospital, NHS Foundation Trust, London, UK
- 3Department of Nuclear Medicine/Imaging, University College London Hospital, NHS Foundation Trust, London, UK
- 4Department of Histopathology, University College London Hospital, NHS Foundation Trust, London, UK
- 5Centre for Respiratory Research, University College London, London, UK
- Correspondence to Dr Neal Navani, Centre for Respiratory Research, University College London, 5 University Street, London WC1E 6JJ, UK; n.navani{at}ucl.ac.uk
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Contributors SMJ, NN and DRL were responsible for the clinical management of the case. NN conceived the idea for the manuscript. L-JES drafted the manuscript. IK contributed to the radiological discussion and provided additional appropriate references. AC and MF reported the original pathological specimens and contributed to the pathological and immunohistochemical aspects of discussion. All authors contributed to manuscript revisions and reviewed the final version.
- Received 2 July 2011
- Accepted 27 October 2011
- Published Online First 21 November 2011
- Non-small cell lung cancer
- lung cancer chemotherapy
- thoracic surgery
- bronchiectasis
- interstitial fibrosis
- lung cancer
- small cell lung cancer
- bronchoscopy
- mesothelioma
Clinical presentation
A 19-year-old student who had never smoked presented with a 6-month history of cough, wheeze, sputum production and generalised fatigue. His exercise tolerance was unaffected and he continued to play rugby competitively. He had a history of childhood asthma and received treatment with inhaled salbutamol with no effect. A chest x-ray revealed a round density at the base of the right lung. A CT chest was performed (figure 1) and subsequently a 68Ga-DOTATATE (1,4,7,10-tetraazacyclododecane-N,N′,N″,N‴-tetraacetic acid-d-Phe(1),Tyr(3)-octreotate) PET-CT (positron emission tomography-CT) was arranged, demonstrating that the mass had a maximum standardised uptake value of 6.6 (figure 2). He was referred for a right lower lobectomy. Histological evaluation of the lobectomy …
