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Lectin-mediated innate defences are important in limiting disease in influenza
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  1. Neelam Kumar
  1. Correspondence to Dr N Kumar, Clinical Infection Unit, St George's Hospital, Blackshaw Road, Tooting, London SW17 0QT, UK; neelamkumar{at}doctors.org.uk

https://doi.org/10.1136/thoraxjnl-2011-200358

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    The innate immune system is an important defence against previously unencountered pathogens. It recognises surface glycans through cell-associated and soluble lectin-mediated defences. This study investigates the effect of blocking these defences on antiviral activities and disease severity in influenza infection.

    Mice were infected with two influenza viruses that differ in the degree of glycosylation of …

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