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Thorax 66:A152 doi:10.1136/thoraxjnl-2011-201054c.209
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P209 Risk factors for respiratory exacerbations in the BOLD study

Abstract P209 Table 1

Risk factors for exacerbations (meta-analysis)

Overall Adjusted OR* (95% CI) Overall I2 (%) p Value for overall I2
Female 1.45 (1.00 to 2.09) 0.0 0.8
Age 0.97 (0.95 to 0.99) 42.1 0.03
Education level 0.95 (0.78 to 1.15) 18.6 0.2
Pack years smoked–per 10 increase 0.90 (0.73 to 1.12) 24.7 0.2
Ex-smoker 1.19 (0.81 to 1.74) 0.0 0.8
Current-smoker 1.37 (0.85 to 2.21) 0.0 0.5
COPD—mild and moderate 2.55 (1.70 to 3.82) 44.0 0.03
COPD—severe and very severe 3.62 (2.11 to 6.18) 0.0 0.6
Doctor Diagnosed Asthma 4.92 (3.77 to 6.42) 0.0 0.9
MMRC Dyspnoea—increased severity 2.14 (1.86 to 2.46) 31.7 0.1
Chronic bronchitis 3.03 (1.97 to 4.66) 14.4 0.3
Post BD FVC 0.90 (0.68 to 1.19) 40.4 0.04
Current biomass exposure 2.67 (1.25 to 5.68) 57.0 0.01
Current dusty job 1.60 (1.16 to 2.22) 15.5 0.3
CVD 1.28 (0.98 to 1.68) 0.0 0.9
Diabetes 1.52 (0.94 to 2.48) 35.3 0.08
Tuberculosis 2.76 (1.10 to 6.91) 65.2 0.001
Childhood respiratory disease 1.52 (0.92 to 2.51) 0.0 0.6
Family history of COPD or asthma 1.35 (1.00 to 1.83) 11.4 0.3
  • * Mutual adjustment for all the risk factors in the table and height and weight, weighted for survey design.

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