SERPINA1 11478G→A variant, serum α1-antitrypsin, exacerbation frequency and FEV1 decline in COPD

Jennifer K Quint; Gavin C Donaldson; Meena Kumari; Philippa J Talmud; John R Hurst

doi:10.1136/thx.2010.152975

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Chronic obstructive pulmonary disease

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SERPINA1 11478G→A variant, serum α₁-antitrypsin, exacerbation frequency and FEV₁ decline in COPD

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	Abstract	Full	Pdf
Feb 2011	141	4	26
Mar 2011	171	3	41
Apr 2011	225	23	68
May 2011	845	29	72
Jun 2011	70	14	31
Jul 2011	53	9	18
Aug 2011	37	8	9
Sep 2011	34	13	15
Oct 2011	32	11	18
Nov 2011	42	12	12
Dec 2011	33	7	10
Jan 2012	53	4	6
Feb 2012	47	5	7
Mar 2012	71	3	4
Apr 2012	50	4	2
May 2012	46	3	4
Jun 2012	43	6	6
Jul 2012	52	3	7
Aug 2012	50	4	3
Sep 2012	35	1	1
Oct 2012	39	3	3
Nov 2012	48	3	5
Dec 2012	41	5	7
Jan 2013	47	7	7
Feb 2013	33	5	3
Mar 2013	45	3	3
Apr 2013	51	3	2
May 2013	31	2	2
Jun 2013	31	0	3
Jul 2013	26	3	2
Aug 2013	30	2	2
Sep 2013	22	0	2
Oct 2013	25	0	1
Nov 2013	20	1	2
Dec 2013	16	4	5
Jan 2014	16	4	3
Feb 2014	29	4	2
Mar 2014	43	6	5
Apr 2014	35	14	8
May 2014	23	12	10
Jun 2014	16	14	13
Jul 2014	21	14	4
Aug 2014	14	24	5
Sep 2014	5	20	10
Oct 2014	19	23	16
Nov 2014	12	7	6
Dec 2014	17	4	2
Jan 2015	16	8	2
Feb 2015	18	4	7
Mar 2015	33	24	11
Apr 2015	31	9	8
May 2015	24	8	4
Jun 2015	13	4	4
Jul 2015	11	17	13
Aug 2015	7	9	4
Sep 2015	15	11	5
Oct 2015	5	5	1
Nov 2015	10	9	5
Dec 2015	12	15	7
Jan 2016	14	8	16
Feb 2016	8	9	11
Mar 2016	6	8	11
Apr 2016	20	10	10
May 2016	16	16	14
Jun 2016	16	10	18
Jul 2016	13	11	22
Aug 2016	11	7	11
Sep 2016	19	4	15
Oct 2016	30	16	7
Nov 2016	19	14	4
Dec 2016	8	4	4
Jan 2017	13	3	8
Feb 2017	7	2	6
Mar 2017	3	9	2
Apr 2017	2	18	5
May 2017	4	19	5
Jun 2017	9	20	5
Jul 2017	11	11	2
Aug 2017	20	18	6
Sep 2017	15	13	4
Oct 2017	19	19	9
Nov 2017	31	21	6
Dec 2017	19	15	3
Jan 2018	23	19	4
Feb 2018	16	12	8
Mar 2018	15	15	7
Apr 2018	12	10	6
May 2018	17	15	5
Jun 2018	20	15	7
Jul 2018	16	8	2
Aug 2018	13	11	2
Sep 2018	9	7	1
Oct 2018	11	11	4
Nov 2018	8	8	4
Dec 2018	8	8	0
Jan 2019	16	12	4
Feb 2019	8	6	4
Mar 2019	13	7	13
Apr 2019	20	11	6
May 2019	12	8	13
Jun 2019	12	10	11
Jul 2019	13	10	17
Aug 2019	10	10	6
Sep 2019	18	16	8
Oct 2019	19	18	14
Nov 2019	8	8	10
Dec 2019	5	5	1
Jan 2020	13	13	7
Feb 2020	13	7	8
Mar 2020	9	7	5
Apr 2020	6	6	6
May 2020	6	6	8
Jun 2020	14	12	5
Jul 2020	16	14	7
Aug 2020	11	8	8
Sep 2020	11	8	1
Oct 2020	20	14	12
Nov 2020	18	13	8
Dec 2020	13	12	11
Jan 2021	13	11	14
Feb 2021	14	14	14
Mar 2021	19	13	6
Apr 2021	11	9	6
May 2021	8	6	5
Jun 2021	9	8	12
Jul 2021	8	5	9
Aug 2021	13	9	10
Sep 2021	12	5	15
Oct 2021	10	8	38
Nov 2021	9	7	36
Dec 2021	16	9	7
Jan 2022	17	8	8
Feb 2022	16	12	5
Mar 2022	22	19	8
Apr 2022	18	15	10
May 2022	24	24	16
Jun 2022	30	27	8
Jul 2022	17	13	7
Aug 2022	26	25	6
Sep 2022	31	30	39
Oct 2022	23	19	10
Nov 2022	13	13	4
Dec 2022	13	9	7
Jan 2023	10	10	12
Feb 2023	6	6	3
Mar 2023	8	8	8
Apr 2023	10	10	10
May 2023	13	11	12
Jun 2023	8	6	7
Jul 2023	14	13	12
Aug 2023	13	13	10
Sep 2023	17	16	11
Oct 2023	14	10	6
Nov 2023	18	16	37
Dec 2023	20	20	9
Jan 2024	20	16	11
Feb 2024	16	15	3
Mar 2024	18	12	65
Total	4482	1641	1527

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