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Thorax 66:855 doi:10.1136/thoraxjnl-2011-200112
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Genetic susceptibility and resistance to tuberculosis

  1. Natalie Settle
  1. Correspondence to Natalie Settle, Department of Accident and Emergency, Watford General Hospital, Vicarage Road, Watford WD18 0HB, UK; nataliesettle{at}doctors.org.uk

This study investigated possible biomarkers of susceptibility and resistance to Mycobacterium tuberculosis, identifying gene expression profiles associated with active tuberculosis (TB). Among a South African cohort, genome-wide transcription profiles of whole blood were obtained from 33 TB patients, 34 healthy donors latently infected with M tuberculosis (LTBI) and 9 healthy …

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