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A 47-year-old male heavy smoker who was an ex-intravenous drugs user presented with gallstones; a preoperatived chest radiograph showed hazy opacity in the right lower lobe. Chest CT revealed in the lower posterior lobes two almost symmetrical areas of consolidation with fat attenuation values (−50 Hounsfield units, figure 1). A broncholaveolar lavage did not provide pathological findings. A transthoracic core needle biopsy showed the pattern of chronic exogenous lipoid pneumonia, with numerous lipid-laden macrophages (figure 2). Upon further investigation, the patient revealed that he had been taking 200 ml of mineral oil daily for 5 years to treat chronic constipation related to methadone treatment.
Lipoid pneumonia can be totally asymptomatic even in heavy smokers and even when lipoid masses are considerable in size.1
Although the diagnosis of lipoid pneumonia is uncommon, it still needs to be considered in adults without anatomical abnormalities predisposing to aspiration.2
The finding of a lung mass surrounded by a crazy-paving pattern on chest CT with density values indicating the presence of fat tissue (Hounsfield units within the −60 to +10 range) should trigger minimally invasive bioptic techniques that may be diagnostic, avoiding surgical approaches.
Triggers for exogenous lipoid pneumonia are usually not recognised as risk factors by patients and as such are not reported.
Competing interests None.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.
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