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Can procalcitonin have a role in reducing antibiotic selective pressure?
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This multicentre, prospective, parallel group randomised trial compared the use of a modified previously published procalcitonin-guided algorithm for antibiotic use with the conventional use of local or national guidelines for antibiotic use over seven intensive care units. A total of 307 patients in the procalcitonin group and 314 in the control group were included. In …