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Lung alert
A potential role for inhibitors of XIAP in the treatment of NSCLC
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  1. S Foster
  1. University Hospitals, Bristol, UK
  1. Correspondence to S Foster, University Hospitals, Bristol, UK; drsjfoster{at}hotmail.com

https://doi.org/10.1136/thx.2010.141093

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    Non-small cell lung cancer (NSCLC) remains the leading cause of cancer mortality worldwide. The pathogenesis of NSCLC involves the evasion of apoptosis. One way this is achieved is via the overexpression of inhibitor of apoptosis proteins (IAPs). Eight human IAPs have been identified, the best characterised and most …

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