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Letters
Upper and lower airway microbiology in cystic fibrosis
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I thank Mainz et al for their recent paper on concordance of upper airway with lower airway microbiology in cystic fibrosis (CF) using nasal lavage.1 However, their claim that their evidence supports a role for the upper airway in the “acquisition and persistence of opportunistic bacteria” in the lower airway does not stand up to scrutiny. Their work is of great interest and addresses an …