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Thorax 64:A16-A17 doi:10.1136/thx.2009.127068
  • Spoken sessions

Causes and outcome in cough

S27 LONG-TERM LOW DOSE ERYTHROMYCIN FOR UNEXPLAINED CHRONIC COUGH: A DOUBLE-BLIND, RANDOMISED, PLACEBO-CONTROLLED TRIAL

1N. Yousaf, 1S. Matos, 2S. S. Birring, 1I. D. Pavord. 1Glenfield Hospital, Leicester, Leicester, UK, 2Kings College Hospital, London, UK

Introduction Unexplained chronic cough is a common condition with no satisfactory treatments. We have previously shown that the induced sputum neutrophil count is independently associated with cough frequency and have speculated that cough is causally linked to neutrophilic airway inflammation. Long-term, low dose macrolide antibiotics reduce neutrophilic airway …


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