Lung cancer: practice and epidemiology
P183 GAMMA SCINTIGRAPHY: REGIONS OF INTEREST IN THE LUNGS. ARE WE BEING CONSISTENT IN WHAT WE ARE MEASURING?
1M. F. Biddiscombe, 2S. Meah, 2P. J. Barnes, 2O. S. Usmani. 1Nuclear Medicine Department, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, UK, 2Airways Disease Section, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, UK
Introduction Two-dimensional gamma scintigraphy (2DGS) is able to quantify the amount of drug delivered from a therapeutic inhaler device to the lungs. To obtain information on the regional lung deposition of inhaled drug, the lung image is divided into several “regions of interest (ROI)” that each represent airways of different sizes. Research groups tend to use their preferred method of ROI, which is often different from other centres. Presently, there is no standard method of defining ROI.
Objectives We compare different methods to determine ROI and ask whether the data generated are comparable.
Methods Using our own lung deposition data with …