Non-atopic persistent asthma in children
- Institute of Child Health, IRCCS Burlo Garofolo, University of Trieste, Trieste, Italy
- Dr G Ventura, Institute of Child Health, IRCCS Burlo Garofolo, University of Trieste, Trieste 34137, Italy; gioviventura{at}gmail.com
Henderson and colleagues1 interestingly describe six different wheezing phenotypes among which persistent wheeze is, they say, less associated with atopy than intermediate or late-onset wheeze (but with similar lung function deficits, suggesting a mixture of structural airway abnormalities and atopic wheeze).
We would like to emphasise the fact that children with persistent asthma without allergic sensitisation (ie, non-atopic …
