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Thorax 64:926-931 doi:10.1136/thx.2008.112466
  • Cystic fibrosis

Cough-generated aerosols of Pseudomonas aeruginosa and other Gram-negative bacteria from patients with cystic fibrosis

Table 2

Microbiology of sputum and CASS samples

Infection status prior to study Expectorated sputum(n = 23) CASS study Voluntary cough (n = 28)/hypertonic saline (n = 20) Tidal study(n = 7)
P aeruginosa not isolated Cleared P aeruginosa (n = 1) 1 3 4
P aeruginosa isolated Chronic P aeruginosa (n = 12 adults, n = 14 children) 21 25* 3
P aeruginosa (unique) 5 7 1
P aeruginosa (AES2) 16 18 2
B cenocepacia isolated Chronic B cenocepacia (n = 1) 1 1 0
  • AES2, Australian Epidemic Strain 2; CASS, cough aerosol sampling system.

  • *Five subjects also cultured additional Gram-negative bacteria in cough aerosols (4 Stenotrophomonas maltophilia and 1 Achromobacter xylosoxidans).


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