99mTechnetium-labelled neutrophil scanning in pneumonia
- 1Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke’s and Papworth Hospitals, Cambridge, UK
- 2Department of Radiology, University of Cambridge School of Clinical Medicine, Addenbrooke’s and Papworth Hospitals, Cambridge, UK
- Professor E R Chilvers, Respiratory Medicine Division, Department of Medicine, University of Cambridge School of Clinical Medicine, Box 157 Addenbrooke’s Hospital, Hill’s Road, Cambridge CB2 2QQ, UK; erc24{at}cam.ac.uk
A 70-year-old man with severe smoking-related chronic obstructive pulmonary disease (COPD) was recruited to a research study to examine the trafficking of 99m-technetium (99mTc)-labelled neutrophils. These studies were undertaken in patients with stable moderate to severe COPD and designed to establish novel methodology (using autologous 99mTc-labelled neutrophils and single photon emission computed tomography (SPECT)) to quantify neutrophil trafficking and accumulation within the lungs of patients with COPD. At the time of scanning he was clinically stable with a C-reactive …
