Use of long-acting β2 agonists in arginine-16 homozygous patients with asthma
- Department of Respiratory Medicine, Glenfield Hospital, Leicester, UK
- Dr R H Green, Department of Respiratory Medicine, Glenfield Hospital, Groby Road, Leicester LE3 9QP, UK; ruth.green{at}uhl-tr.nhs.uk
We read with interest the study by Palmer and colleagues.1 Their findings suggest that patients who are Arg/Arg homozygous at position 16 of the β2 adrenoceptor may be at increased risk of asthma exacerbations, particularly when treated with inhaled salmeterol. These results add to the body of evidence questioning the safety of long-acting β2 agonists in this subgroup of …
