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Early detection of cancer: lessons from lung cancer CT screening
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Black et al1 reviewed 12 studies of CT screening for lung cancer published up to 2004 and concluded that there is insufficient evidence that CT screening might be clinically effective in reducing mortality from lung cancer.
This study was published immediately after two discordant studies by Henschke et al2 and Bach et al.3 The first study, in spite of the lack of total or disease-specific mortality rates for the screened population, concluded that low-dose CT screening could lead to a therapeutic strategy that resulted in a 10-year survival of 88% for patients with stage I disease.2 The second, in line with Black et …
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