Intrabullous blood injection for lung volume reduction
- Division of Pulmonary Medicine, Department of Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan
- Dr S Kanoh, Division of Pulmonary Medicine, Department of Medicine, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan; kanoh{at}ndmc.ac.jp
- Received 26 July 2007
- Accepted 24 October 2007
Abstract
Bronchoscopic treatment for emphysematous lung diseases has attracted clinical attention, and several different approaches are being investigated. We present a case of emphysematous bullae that was effectively treated with a newly developed bronchoscopic intervention, autologous blood injection. A 59-year-old man was referred to our institution with exertional dyspnoea. Chest CT showed emphysema and bullae with a diameter of 12 cm in the right upper lobe. Bronchoscopic treatment was introduced as an alternative to surgery. Autologous blood and fibrinogen solution were infused into bullae via the transbronchial catheter, under fluoroscopic guidance. Post-treatment CT showed marked contraction of bullae to a diameter of 3 cm, corresponding to a volume reduction of 800 ml on body plethysmography. A significant reduction in dyspnoea was also noted. This therapeutic approach is less invasive and may represent a good option for reducing lung volume.
Footnotes
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Competing interests: None.
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Ethics approval: The Institutional Review Board of Ethics approved the treatment protocol.
