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Reproducibility of dynamically represented acoustic lung images from healthy individuals
  1. T M Maher1,
  2. M Gat2,
  3. D Allen3,
  4. A Devaraj3,
  5. A U Wells1,
  6. D M Geddes1
  1. 1Department of Respiratory Medicine, The Royal Brompton Hospital, London, UK
  2. 2Deep Breeze Ltd, North Industrial Park, Or Akiva, Israel
  3. 3Department of Radiology, The Royal Brompton Hospital, London, UK
  1. Dr T M Maher, Department of Respiratory Medicine, Interstitial Lung Disease Unit, Royal Brompton Hospital, Sydney St, London SW3 6NP, UK; t.maher{at}ucl.ac.uk

Abstract

Background and aim: Acoustic lung imaging offers a unique method for visualising the lung. This study was designed to demonstrate reproducibility of acoustic lung images recorded from healthy individuals at different time points and to assess intra- and inter-rater agreement in the assessment of dynamically represented acoustic lung images.

Methods: Recordings from 29 healthy volunteers were made on three separate occasions using vibration response imaging. Reproducibility was measured using quantitative, computerised assessment of vibration energy. Dynamically represented acoustic lung images were scored by six blinded raters.

Results: Quantitative measurement of acoustic recordings was highly reproducible with an intraclass correlation score of 0.86 (very good agreement). Intraclass correlations for inter-rater agreement and reproducibility were 0.61 (good agreement) and 0.86 (very good agreement), respectively. There was no significant difference found between the six raters at any time point. Raters ranged from 88% to 95% in their ability to identically evaluate the different features of the same image presented to them blinded on two separate occasions.

Conclusion: Acoustic lung imaging is reproducible in healthy individuals. Graphic representation of lung images can be interpreted with a high degree of accuracy by the same and by different reviewers.

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Footnotes

  • Competing interests: Equipment for the study was provided by DeepBreeze Ltd. The Royal Brompton Hospital received a grant from DeepBreeze Ltd to cover the costs of conducting the study. MG is an employee of DeepBreeze Ltd. TM has received reimbursement from DeepBreeze Ltd for travel and accommodation costs following attendance at a symposium.

  • Ethics approval: This study was approved by The Royal Brompton, Harefield and NHLI Research Ethics Committee.