This is the first study to evaluate the pathogenic role of the novel chitinase-like protein YKL-40 in asthma. In experimental models, YKL-40 and chitinases promoted airway inflammation through type 2 helper T cells. This study investigated serum YKL-40 levels in asthma, including assessing relationships with disease severity, airway YKL-40 levels and airway remodelling. …
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Online ISSN 1468-3296
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