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Soluble interleukin 6 receptor is raised in sleep-related breathing disorder
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  1. T Sathyamoorthy
  1. William Harvey Hospital, Ashford, Kent, UK; tarasathyamoorthy@yahoo.co.uk

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    ▴ Mehra R, Storfer-Isser A, Kirchner HL, et al. Soluble interleukin 6 receptor: a novel marker of moderate to severe sleep-related breathing disorder. Arch Intern Med2006;166:1725–31.
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    Cardiovascular disease (CVD) is increased in moderate to severe sleep-related breathing disorder (SRBD). Interleukin 6 (IL6) promotes atherogenesis and elevated levels occur in SRBD. Soluble IL6 receptor (sIL6R) exerts widespread effects compared with IL6 alone. The authors examined the relationship between SRBD severity, IL6 and sIL6R levels, and morning and evening variability …

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